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Unusual global outbreak of monkeypox: what should we do?

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 507-517 doi: 10.1007/s11684-022-0952-z

Abstract: Recently, monkeypox has become a global concern amid the ongoing COVID-19 pandemic. Monkeypox is an acute rash zoonosis caused by the monkeypox virus, which was previously concentrated in Africa. The re-emergence of this pathogen seems unusual on account of outbreaks in multiple nonendemic countries and the incline to spread from person to person. We need to revisit this virus to prevent the epidemic from getting worse. In this review, we comprehensively summarize studies on monkeypox, including its epidemiology, biological characteristics, pathogenesis, and clinical characteristics, as well as therapeutics and vaccines, highlighting its unusual outbreak attributed to the transformation of transmission. We also analyze the present situation and put forward countermeasures from both clinical and scientific research to address it.

Keywords： monkeypox     poxviruses     vaccine     infectious diseases    

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Unusual global outbreak of monkeypox: what should we do?

Journal Article